Chelerythrine
Update£º2014-01-23 09:10:14 Click£º
- Product Brand AUS
- Product type
Description
Product name: Chelerythrine
Plant source: Toddalia asiatica (L.)Lam.
Molecular formula: C21H18ClNO4 ¡¡¡¡
Molecular weight: 383.83
Characteristics: light yellow powder or white powder, melting point: 195-205¡ãC , 207¡æ(lmol ethanol) or 250¡æ(0.5mol water)
Specifications: 50£¥¡¢90%¡¢95%¡¢98£¥ HPLC
Biological Activity:
Potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 ¦ÌM) or Bad proteins and stimulates apoptosis.
Packing: 1kg/ aluminum bag
25kgs/ fiber durm or according to customer's demand
Shelf life: 2 years
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