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Palonosetron

Update£º2014-01-31 16:26:12 Click£º
  • Product Brand AUS
  • Product type
Description
Product name: Palonosetron

Synonyms:2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one

Molecular formula: 
C19H24N2O

Molecular weight: 296.41

Appearance: White crystalloid powder

CAS: 135729-61-2

Assay£º99%

Indication: Used to prevent acute and late sex vomiting caused by the chemotherapy which induces intermediate or high vomiting.

Pharmacology: Serotonin (5 - Hydroxytryptamine, 5 - HT) as a kind of indoles procedures, is one of human body key neural medium. Serotonin can activate 5 - HT3 receptors which produces vomiting reflex. Palonosetron on 5-HT3 receptors have a strong affinity, thereby preventing the vomiting reflex.
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