Leucovorin Calcium
Update£º2014-01-31 16:06:38 Click£º
- Product Brand AUS
- Product type
Description
Product name: Leucovorin CalciumSynonyms: Folinic acid calcium salt;
Assay£º 99%
Molecular formula: C20H21N7O7.Ca
Molecular weight: 511.51
Appearance: Small yellow to yellow crystal or amorphous powder
CAS: 1492-18-8
Indication: Used to remove receie methotrexate amino and methotrexate caused by excessive toxic reaction, it can also be used to treat giant RBC anemia.
Pharmacology: This product is the formyl tetrahydrofolate derivatives, mainly for high-dose methotrexate and other folic acid antagonists rescue. The main role of methotrexate with dihydrofolate reductase binding, blocking the dihydrofolate into tetrahydrofolate to inhibit DNA synthesis. This product into the body, through tetrahydrofolate reductase into tetrahydrofolate which can effectively combat the toxicity caused by methotrexate, but no significant effect on the existing methotrexate neurotoxicity.
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