Cytarabine
Update£º2014-01-29 16:18:17 Click£º
- Product Brand AUS
- Product type
Description
Product name: CytarabineSynonym: cytosine arabinoside
Molecular formula: C9H13N3O5
Assay£º99%
Molecular weight: 243.2166
CAS number: 205-705-9
Appearance: white or all most white crystal powder
Indication£º
Mainly used for acute leukemia: acute myeloid leukemia on the best of the acute monocytic leukemia and acute lymphoblastic leukemia andeffective.
Generalapplications are combined with other drugs. Malignant lymphoma, lung cancer,gastrointestinal cancer, head and neck cancer, etc.
Pharmacology:
This product is a major role in cell proliferation and S phase of pyrimidineantimetabolites. Cytarabine inhibit DNA synthesis, interfere with cell proliferation. Ara-C enters the body through kinase phosphorylation and changed muscle cytarabinecytarabine triphosphate diphosphate. Cytarabine triphosphate muscles can inhibit the DNA polymerase the synthesis of strongly¡£
Ara-C caninhibit diphosphate diphosphate diphosphate cytidine into deoxycytidine¡£So it can inhibit aggregation and synthesis of DNA
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