Paclitaxel
Update£º2014-01-31 16:23:27 Click£º
- Product Brand AUS
- Product type
Description
Product name: PaclitaxelSynonyms:
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;
Taxal; Taxol A
Molecular formula: C47H51NO14
Molecular weight: 853.92
Appearance: White crystals
CAS: 33069-62-4
Assay£º99%
Indication: Suitable for ovarian cancer and breast cancer, for lung cancer, colon cancer, melanoma, head and neck cancer, lymphoma, brain also have certain curative effect.
Pharmacology: Tubulin / microtubule system is a major target site of taxol, it can promote microtubule polymerization, restrain microtubules degradation, making the cell division block in the G2 / M period, also can induce apoptosis in various cancer cells, and through inhibition of tubulin and microtubules composed of tubulin dimer dynamic equilibrium to induce tumor cell apoptosis.
More
